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Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound  to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME - ScienceDirect
Crystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYME - ScienceDirect

Malvika Sharan on Twitter: "These 2 talks were public seminars at  @NCBS_Bangalore. It's inspiring to see how Hari and Norman share their  Scientific enthusiasm and contribute to each other's research in disorder
Malvika Sharan on Twitter: "These 2 talks were public seminars at @NCBS_Bangalore. It's inspiring to see how Hari and Norman share their Scientific enthusiasm and contribute to each other's research in disorder

Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and  Selective Detection of Targets Modified by Covalent Probes,Analytical  Chemistry - X-MOL
Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes,Analytical Chemistry - X-MOL

Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI |  Department of Cancer Biology
Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI | Department of Cancer Biology

Sirano Dhe-Paganon's research works | Brandeis University, Waltham and  other places
Sirano Dhe-Paganon's research works | Brandeis University, Waltham and other places

Selective USP7 inhibition elicits cancer cell killing through a  p53-dependent mechanism | Scientific Reports
Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism | Scientific Reports

Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme  Inhibitor MLN4924 in Human Leukemic Cells
Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Human Leukemic Cells

Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands -  Remillard - 2017 - Angewandte Chemie International Edition - Wiley Online  Library
Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands - Remillard - 2017 - Angewandte Chemie International Edition - Wiley Online Library

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI |  Department of Cancer Biology
Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI | Department of Cancer Biology

Crystal Structure of the HNF4α Ligand Binding Domain in Complex with  Endogenous Fatty Acid Ligand* - Journal of Biological Chemistry
Crystal Structure of the HNF4α Ligand Binding Domain in Complex with Endogenous Fatty Acid Ligand* - Journal of Biological Chemistry

Core Facilities - Dana-Farber Cancer Institute | Boston, MA
Core Facilities - Dana-Farber Cancer Institute | Boston, MA

PDF) Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding  (PH-PTB) Targeting Region of Insulin Receptor Substrate 1
PDF) Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding (PH-PTB) Targeting Region of Insulin Receptor Substrate 1

Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI |  Department of Cancer Biology
Sirano DHE-PAGANON | Dana-Farber Cancer Institute, Boston | DFCI | Department of Cancer Biology

Gunning Group | Collaborators
Gunning Group | Collaborators

Loss of heterozygosity of essential genes represents a widespread class of  potential cancer vulnerabilities | Nature Communications
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities | Nature Communications

by Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk, Justin M - ppt  download
by Georg E. Winter, Dennis L. Buckley, Joshiawa Paulk, Justin M - ppt download

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal  Kv4 channels | Scientific Reports
Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels | Scientific Reports

Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center
Facility - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Tour — McLellan Lab
Tour — McLellan Lab

Publications - Sirano Dhe Paganon, PhD - Structural & Chemical Biology  Center
Publications - Sirano Dhe Paganon, PhD - Structural & Chemical Biology Center

Interest Groups - Dana-Farber Cancer Institute | Boston, MA
Interest Groups - Dana-Farber Cancer Institute | Boston, MA